New Ultrapure Methylene Chloride Enhances Trace Analysis Performance by GC and GC/MS

FAIR LAWN, N.J.--Researchers can now take advantage of enhancements to ultrapure methylene chloride solvents that deliver an interference-free baseline in chromatograms for better detection of trace levels of target analytes in identifying compounds of interest. This is particularly important for environmental testing of polycyclic aromatic hydrocarbons (PAHs), as well as pesticides in food, water, and soil samples.

“With our new Optima and GC Resolv solutions, we implemented a quality by design (QbD) approach to manufacture ultrapure methylene chloride in order to provide researchers with an extraction solvent that consistently shows an interference-free baseline during GC analysis.”

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Fisher Chemical Optima and GC Resolv Methylene Chloride solutions are designed specifically for customers using methylene chloride in pharmaceutical, environmental, food and chemical industries applications. These solutions can be used as an extraction solvent for identifying and quantifying by gas chromatography (GC-MS, GC-FID, and GC-ECD) trace amounts of volatile organic compounds.

“Instrumentation advances are leading to lower analyte detection limits,” said Stephen Roemer, global director, R&D, Fisher Chemical, Thermo Fisher Scientific. “With our new Optima and GC Resolv solutions, we implemented a quality by design (QbD) approach to manufacture ultrapure methylene chloride in order to provide researchers with an extraction solvent that consistently shows an interference-free baseline during GC analysis."

The enhanced grades of methylene chloride ensure a high-quality solvent from time of manufacturing to when the analyst first opens the container. Extended shelf life studies confirm that solvent quality is sustained even in large-volume returnable containers, such as FisherPak. Additional enhancements include:

  • High purity: raw material screening, optimized distillation processes and packaging innovations provide extremely clean product for critical GC applications.
  • Lot-to-lot consistency: a QbD (Quality by Design) approach to manufacturing, coupled with stringent quality control procedures, ensures product quality in every bottle.
  • Outstanding performance: interference-free baseline during trace analysis of standards on gas chromatography instruments with various detectors (GC-MS, GC-FID and GC-ECD) at 1000-fold concentration.

The new solvents work well with many Thermo Scientific instruments; including the Thermo Scientific TRACE 1310 Gas Chromatograph with Thermo Scientific TSQ Quantum Ultra triple quadrupole mass spectrometer. For more information on Fisher Chemical Methylene Chloride Optima and GC Resolv, please visit www.fishersci.com/fisherchemical.

About Thermo Fisher Scientific

Thermo Fisher Scientific Inc. is the world leader in serving science, with revenues of $17 billion and 50,000 employees in 50 countries. Our mission is to enable our customers to make the world healthier, cleaner and safer. We help our customers accelerate life sciences research, solve complex analytical challenges, improve patient diagnostics and increase laboratory productivity. Through our four premier brands – Thermo Scientific, Life Technologies, Fisher Scientific and Unity Lab Services – we offer an unmatched combination of innovative technologies, purchasing convenience and comprehensive support. For more information, please visit www.thermofisher.com.

 

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Thermo Fisher Scientific
Marcia Goff, +1-508-902-7041
marcia.goff@thermofisher.com

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